SCHEMBL29293167

SCHEMBL29293167

CC1(C)c2ccccc2-c2ccc(-c3ccc(-c4cccc5c4sc4c(-c6cc(-c7ccncc7)cc(-c7ccncc7)c6)cccc45)cc3)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.44
BACE1 P56817 1/20 0.39
BACE2 Q9Y5Z0 1/20 0.39
PDE10A Q9Y233 2/20 0.35
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
PIK3CA P42336 1/20 0.34
TDO2 P48775 1/20 0.34
CDC7 O00311 1/20 0.33
ROCK2 O75116 1/20 0.33
MAP4K4 O95819 1/20 0.33
PRKACA P17612 1/20 0.33
CDK2 P24941 1/20 0.33
GSK3B P49841 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
ALOX5 P09917 1/20 0.33
IMPDH2 P12268 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29293165 0.97 PDK2 (0.43) PDK2BACE1BACE2PDE10AMAPK11
SCHEMBL17057191 0.86 PDK2 (0.42) PDK2ALOX5LIMK1
SCHEMBL24493234 0.85 PDK2 (0.55) PDK2PIK3CACDC7ROCK2MAP4K4
SCHEMBL29293166 0.85 PDK2 (0.37) PDK2BACE1BACE2PDE10AMAPK11
SCHEMBL10018859 0.84 ALOX5 (0.44) PDK2TDO2ALOX5LIMK1
SCHEMBL17425649 0.84 LIMK1 (0.35) PDK2ALOX5LIMK1
SCHEMBL17425448 0.84 LIMK1 (0.35) PDK2ALOX5LIMK1
SCHEMBL30022622 0.84 LIMK1 (0.35) PDK2ALOX5LIMK1
SCHEMBL29293044 0.83 PDK2 (0.46) PDK2BACE1PDE10AALOX5CYP17A1
SCHEMBL25213447 0.83 PDK2 (0.34) PDK2ALOX5LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same OR10J3, ORMDL3, OR51E2 PDK2 2309/4885BACE1 1713/4885BACE2 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.