Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.62 |
| ▸ | PIK3C3 | Q8NEB9 | 11/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294998 | 1.00 | NLRP3 (0.62) | NLRP3PIK3C3PDE4DATRATM | |
| SCHEMBL29294968 | 1.00 | NLRP3 (0.62) | NLRP3PIK3C3PDE4DATRATM | |
| SCHEMBL29295119 | 0.89 | NLRP3 (0.49) | NLRP3PIK3C3PDE4DATRATM | |
| SCHEMBL29295120 | 0.89 | NLRP3 (0.49) | NLRP3PIK3C3PDE4DATRATM | |
| SCHEMBL29295066 | 0.89 | NLRP3 (0.49) | NLRP3PIK3C3ATR | |
| SCHEMBL29295057 | 0.88 | NLRP3 (0.60) | NLRP3PIK3C3ATRATMMTOR | |
| SCHEMBL29295141 | 0.85 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL29295144 | 0.85 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL29295142 | 0.85 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL29294062 | 0.84 | NLRP3 (0.69) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |