Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.85 |
| ▸ | NR1H2 | P55055 | 15/20 | 0.84 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.84 |
| ▸ | POLA1 | P09884 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270695 | 1.00 | SOD1 (0.85) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL20561073 | 1.00 | SOD1 (0.85) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL29493568 | 1.00 | SOD1 (0.85) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL20561070 | 1.00 | SOD1 (0.85) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL30427212 | 1.00 | SOD1 (0.85) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL6312666 | 0.92 | NR1H2 (1.00) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL6312669 | 0.92 | NR1H2 (1.00) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL20561396 | 0.92 | NR1H2 (1.00) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL7767289 | 0.87 | POLA1 (0.81) | SOD1NR1H2NR1H3POLA1 | |
| SCHEMBL24177920 | 0.87 | POLA1 (0.81) | SOD1NR1H2NR1H3POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883926-B1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS | REGENERON PHARMA (US) | 2024-07-10 | — | — | EP | disclosed |