Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 10/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 2/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 2/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 2/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | DYRK3 | O43781 | 1/20 | 1.00 |
| ▸ | CCNT1 | O60563 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harmine SCHEMBL29440552 | 1.00 | MAOA (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL30510974 | 1.00 | MAOA (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL9481427 | 1.00 | MAOA (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL29941920 | 1.00 | MAOA (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL1469013 | 0.98 | KLK7 (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL16099771 | 0.98 | MAOA (0.97) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL30726913 | 0.98 | KLK7 (1.00) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL31500130 | 0.97 | KLK7 (0.97) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL669625 | 0.97 | KLK7 (0.97) | MAOADYRK1AACHECCNB2CDK1 | |
| Harmine SCHEMBL4907423 | 0.97 | KLK7 (0.97) | MAOADYRK1AACHECCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5014 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137652-A1 | Composition Comprising Non-Phosphorylated Tryptamine | SINTALICA S R L (IT) | 2026-05-21 | — | — | US | claimed |
| US-12630803-B2 | Method of increasing proliferation of pancreatic beta cells, treatment method, and composition | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2026-05-19 | — | — | US | claimed |
| US-20260091047-A1 | THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS | NATIVE CODE BIO LLC (US) | 2026-04-02 | — | — | US | claimed |
| EP-4351506-B1 | LIPID CRYSTALLINE COMPOSITIONS WITH ENHANCED STABILITY FOR TOPICAL DELIVERY OF ACTIVE AGENT COMBINATIONS | ANKH LIFE SCIENCES LTD (IE) | 2026-04-01 | — | — | EP | claimed |
| EP-4717479-A2 | SELECTING DIFFERENT SUSPENSION TUNES VIA A MANUALLY OPERATED SWITCH | Fox Factory, Inc. (US) | 2026-04-01 | — | — | EP | claimed |
| US-12558358-B2 | N-(furan-2-ylmethyl)-7H-purin-6-amine for treatment of circadian rhythm diseases, disorders and dysfunctions | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2026-02-24 | — | — | US | claimed |
| US-20260007643-A1 | HIGHLY SOLUBLE FORMULATIONS OF HARMINE | RECONNECT LABS AG (CH) | 2026-01-08 | — | — | US | claimed |
| US-20250339403-A1 | Tryptamine Formulations and Uses Thereof | Natural MedTech Pty Ltd (AU) | 2025-11-06 | — | — | US | claimed |
| US-20250339483-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON INTRANASAL ADMINISTRATION, AND USES THEREOF | AGS THERAPEUTICS SAS (FR) | 2025-11-06 | — | — | US | claimed |
| US-20250304688-A1 | Methods and Compositions Comprising Anti-CD3 Antibodies and DYRK1A Inhibitors for Treating Diabetes | PROVENTION BIO, INC. (US) | 2025-10-02 | — | — | US | claimed |
| WO-2005053703-A1 | COMBINATION THERAPY FOR DEMENTIA, DEPRESSION AND APATHY | SHELDON LESLIE JAMES (CA) | 2005-06-16 | — | — | WO | claimed |
| US-20040266637-A1 | Aqueous buffered fluoride-containing etch residue removers and cleaners | VERSUM MATERIALS US, LLC | 2004-12-30 | — | — | US | claimed |
| CN-1542015-A | Preparation method and application of harmel seed alkaloid | 河北以岭医药研究院有限公司 | 2004-11-03 | — | — | CN | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-20020102246-A1 | Antimicrobial compositions | NOVOZYMES A/S (DK) | 2002-08-01 | — | — | US | claimed |
| US-20020019421-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-02-14 | — | — | US | claimed |
| WO-2001084937-A1 | OXIDOREDUCTASE MEDIATED ANTIMICROBIAL ACTIVITY | NOVOZYMES A/S (DK) | 2001-11-15 | — | — | WO | claimed |
| US-5591738-A | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof | NDA INTERNATIONAL, INC. (US) | 1997-01-07 | — | — | US | claimed |
| WO-1991014184-A1 | BETA CARBOLINES AS VITAL STAINS FOR NEUROTRANSMITTER SYSTEMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-09-19 | — | — | WO | claimed |
| CN-1034135-A | The preparation method of peganum harmala seed extract | HOSPITAL NO 2 ATTACHED TO XINJ (CN) | 1989-07-26 | — | — | CN | claimed |