Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295324 | 0.84 | KLK7 (0.44) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL29295325 | 0.84 | KLK7 (0.44) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL29295612 | 0.83 | KLK7 (0.42) | KLK7PARP1GHSRDPP4GAA | |
| SCHEMBL29295326 | 0.83 | KLK7 (0.48) | KLK7PARP1DPP4GAATHRB | |
| SCHEMBL29295636 | 0.83 | KLK7 (0.44) | KLK7PARP1GHSRGAATHRB | |
| SCHEMBL6610814 | 0.81 | DAGLA (0.54) | KLK7PARP1FKBP1ADPP4MEN1 | |
| SCHEMBL20129716 | 0.81 | DAGLA (0.54) | KLK7PARP1FKBP1ADPP4MEN1 | |
| SCHEMBL20014393 | 0.81 | KLK7 (0.47) | KLK7PARP1MMP1MMP3MMP9 | |
| SCHEMBL7908488 | 0.80 | KLK7 (0.52) | KLK7PARP1FKBP1ADPP4MEN1 | |
| SCHEMBL4664791 | 0.80 | KLK7 (0.52) | KLK7PARP1FKBP1ADPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |