Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295612 | 0.83 | KLK7 (0.42) | KLK7PARP1GHSRGAATHRB | |
| SCHEMBL29295628 | 0.83 | KLK7 (0.49) | KLK7PARP1GHSRGAATHRB | |
| SCHEMBL30987191 | 0.82 | PARP1 (0.44) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL29295326 | 0.81 | KLK7 (0.48) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL29295324 | 0.78 | KLK7 (0.44) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL29295325 | 0.78 | KLK7 (0.44) | KLK7PARP1GAATHRBSMN1; SMN2 | |
| SCHEMBL28549464 | 0.76 | PARP1 (0.46) | KLK7PARP1STSNR1H2NR1H3 | |
| SCHEMBL28795613 | 0.76 | NR1D1 (0.46) | KLK7PARP1GHSRSTSNR1H2 | |
| SCHEMBL29007899 | 0.76 | NR1D1 (0.46) | KLK7PARP1GHSRSTSNR1H2 | |
| SCHEMBL28795615 | 0.76 | NR1D1 (0.46) | KLK7PARP1GHSRSTSNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |