SCHEMBL29299665

SCHEMBL29299665

CC(C)CCCNC(=O)[C@H](N)CCCNC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
OTC P00480 1/20 0.40
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
NOD1 Q9Y239 1/20 0.39
RRM1 P23921 1/20 0.38
ALDH1A1 P00352 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
FOLH1 Q04609 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29299811 0.98 DPP7 (0.45) DPP7SMN1; SMN2TP53OTCGNAI3
SCHEMBL29299797 0.96 DPP7 (0.46) DPP7SMN1; SMN2TP53GNAI3GNAO1
SCHEMBL29299824 0.96 DPP7 (0.43) DPP7SMN1; SMN2TP53OTCGNAI3
SCHEMBL29299823 0.90 SMN1; SMN2 (0.37) DPP7SMN1; SMN2TP53OTCALDH1A1
SCHEMBL29300536 0.90 DPP7 (0.50) DPP7SMN1; SMN2TP53OTCGNAI3
SCHEMBL24590552 0.89 SMN1; SMN2 (0.50) SMN1; SMN2TP53ALDH1A1SIGMAR1FOLH1
SCHEMBL29299668 0.87 NOD1 (0.37) DPP7SMN1; SMN2TP53NOD1SIGMAR1
SCHEMBL27331978 0.87 NOD1 (0.37) DPP7SMN1; SMN2TP53OTCGNAI3
SCHEMBL29300523 0.86 DPP7 (0.56) DPP7GNAI3GNAO1GNAI1NOD1
SCHEMBL23824133 0.85 SMN1; SMN2 (0.49) SMN1; SMN2TP53ALDH1A1SIGMAR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R DPP7 1196/4885SMN1; SMN2 3725/4885TP53 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.