Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926999 | 0.81 | MEN1 (0.50) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5309948 | 0.75 | MEN1 (0.61) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL821620 | 0.75 | KMT2A (0.76) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5304888 | 0.74 | MEN1 (0.56) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5309940 | 0.73 | MEN1 (0.49) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5312400 | 0.72 | MEN1 (0.48) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5312251 | 0.72 | MEN1 (0.48) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5309396 | 0.71 | EGLN1 (0.43) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5308672 | 0.70 | MEN1 (0.47) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5311723 | 0.70 | HIF1A (0.48) | MEN1KMT2ARXFP1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227232-A1 | METHODS FOR INHIBITING T HELPER CELL DIFFERENTIATION | Fibrogen, Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009075822-A1 | METHODS FOR INHIBITING T HELPER CELL DIFFERENTIATION | FIBROGEN, INC. (US) | 2009-06-18 | — | — | WO | disclosed |