Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605375 | 0.80 | TDP1 (0.45) | TDP1TAAR1 | |
| SCHEMBL27282980 | 0.78 | TDP1 (0.47) | TDP1TAAR1 | |
| SCHEMBL510995 | 0.77 | TDP1 (0.49) | TDP1 | |
| SCHEMBL7285985 | 0.72 | TDP1 (0.40) | TDP1TAAR1 | |
| SCHEMBL27862434 | 0.72 | TAAR1 (0.47) | TAAR1 | |
| SCHEMBL7285992 | 0.72 | TDP1 (0.40) | TDP1TAAR1 | |
| SCHEMBL4487051 | 0.70 | TDP1 (0.48) | TDP1 | |
| SCHEMBL4630233 | 0.70 | TAAR1 (0.41) | TDP1TAAR1 | |
| SCHEMBL4487058 | 0.70 | TDP1 (0.48) | TDP1 | |
| SCHEMBL511996 | 0.69 | TDP1 (0.34) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284169-B1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |