Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7638960 | 0.98 | HDAC6 (0.54) | HDAC6APPTDP1THRBALOX15 | |
| SCHEMBL15546688 | 0.84 | PRSS1 (0.41) | HDAC6THRBPRSS1ALDH1A1KDM4E | |
| SCHEMBL124591 | 0.82 | HDAC6 (0.71) | HDAC6TDP1THRBALOX15TP53 | |
| SCHEMBL2929676 | 0.81 | CYP3A4 (0.40) | HDAC6APPTDP1THRBALOX15 | |
| SCHEMBL3637289 | 0.80 | HDAC6 (0.59) | HDAC6APPTDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL6273139 | 0.80 | CYP3A4 (0.39) | HDAC6APPTDP1THRBALOX15 | |
| SCHEMBL2722710 | 0.80 | ALDH1A1 (0.56) | HDAC6APPTDP1THRBALOX15 | |
| SCHEMBL1497919 | 0.79 | HDAC6 (0.58) | HDAC6TDP1THRBALOX15TP53 | |
| SCHEMBL7137884 | 0.77 | HDAC6 (0.65) | HDAC6TDP1THRBALOX15TP53 | |
| SCHEMBL2925414 | 0.77 | MAPT (0.44) | HDAC6APPTDP1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983996-A1 | Cationic ortho-phenylenediamines, their use for oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | claimed |
| EP-1728500-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1073407-B1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE ORQUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | OREAL (FR) | 2005-04-20 | — | — | EP | disclosed |
| EP-0983996-A1 | Cationic ortho-phenylenediamines, their use for oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |