Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22848880 | 0.85 | CYP2D6 (0.54) | CYP2D6TSHRCYP1A2USP2HIF1A | |
| SCHEMBL23696162 | 0.81 | CYP2D6 (0.44) | CYP2D6TSHRCYP1A2USP2HIF1A | |
| SCHEMBL24710303 | 0.79 | OPRM1 (0.46) | CYP2D6CYP1A2CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL23560014 | 0.78 | CYP2D6 (0.61) | CYP2D6TSHRCYP1A2USP2HIF1A | |
| SCHEMBL24673717 | 0.78 | CYP2D6 (0.47) | CYP2D6TSHRCYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL23568464 | 0.77 | OPRM1 (0.41) | CYP2D6TSHRCYP1A2USP2HIF1A | |
| SCHEMBL22848884 | 0.77 | CYP2D6 (0.52) | CYP2D6TSHRCYP1A2USP2HIF1A | |
| SCHEMBL23807179 | 0.77 | CYP2D6 (0.46) | CYP2D6TSHRCYP1A2USP2CYP2C19 | |
| SCHEMBL20669225 | 0.76 | NAMPT (0.39) | CYP2D6TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL25468791 | 0.74 | PDCD1 (0.38) | CYP2D6TSHRCYP1A2USP2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |