Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.58 |
| ▸ | TNF | P01375 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057235 | 0.95 | IL1B (0.66) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057276 | 0.88 | IL1B (0.65) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057135 | 0.85 | IL1B (0.66) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057281 | 0.83 | IL1B (0.60) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057410 | 0.83 | IL1B (0.64) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057180 | 0.83 | IL1B (0.60) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057269 | 0.82 | IL1B (0.73) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057277 | 0.81 | IL1B (0.73) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057305 | 0.81 | IL1B (0.66) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31057345 | 0.81 | IL1B (0.68) | IL1BNLRP3TNFKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |