SCHEMBL29308223

SCHEMBL29308223

CO[Si](C)(CCCN1CCN(CCC[Si](OC)(OC)OC)CC1)OC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.34
CSNK2B P67870 2/20 0.34
CSNK2A1 P68400 2/20 0.34
CSNK2A3 Q8NEV1 2/20 0.34
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.32
KCNH2 Q12809 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31
PAOX Q6QHF9 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11897269 0.92 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL4361438 0.90 MAPT (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL11897301 0.90 MAPT (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL8083018 0.88 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL302762 0.88 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL4062217 0.87 CSNK2A2 (0.33) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL14814163 0.85 MAPK1 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3HSD17B10
SCHEMBL128337 0.85 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3PAOX
SCHEMBL10598698 0.84 KCNH2 (0.40) MAPTKCNH2PAOXLMNAHTR1A
SCHEMBL1995694 0.84 HRH3 (0.44) MAPTKCNH2ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037432-B2 Method for preparing modified and conjugated diene-based polymer and modified and conjugated diene-based polymer prepared using the same LG CHEM, LTD. (KR) 2024-07-16 US disclosed