SCHEMBL11897269

SCHEMBL11897269

CO[Si](C)(CCCN1CCN(CCC[Si](C)(OC)OC)CC1)OC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.38
CSNK2B P67870 2/20 0.38
CSNK2A1 P68400 2/20 0.38
CSNK2A3 Q8NEV1 2/20 0.38
PAOX Q6QHF9 1/20 0.34
MAPT P10636 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KCNH2 Q12809 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083018 0.96 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3PAOX
SCHEMBL128337 0.92 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3PAOX
SCHEMBL29308223 0.92 CSNK2A2 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3PAOX
SCHEMBL14814163 0.92 MAPK1 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1
SCHEMBL1995694 0.91 HRH3 (0.44) MAPTALDH1A1HRH3KCNH2SMN1; SMN2
SCHEMBL28851634 0.90 ALOX15 (0.48) CSNK2A2CSNK2BCSNK2A1CSNK2A3SIGMAR1
SCHEMBL611596 0.90 HRH3 (0.48) MAPTALDH1A1HRH3KCNH2SMN1; SMN2
SCHEMBL2852223 0.90 HRH3 (0.48) MAPTALDH1A1HRH3KCNH2SMN1; SMN2
SCHEMBL612240 0.88 SMN1; SMN2 (0.48) USP2ALDH1A1HPGDSIGMAR1HRH3
SCHEMBL4059422 0.86 CSNK2A2 (0.33) CSNK2A2CSNK2BCSNK2A1CSNK2A3PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484701-B1 PRODUCTION METHOD FOR MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND MODIFIED CONJUGATED DIENE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2017-11-08 EP disclosed
US-8816014-B2 Method for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and modified conjugated diene-based polymer composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-08-26 US disclosed
US-20120277369-A1 Method for Producing Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer, and Modified Conjugated Diene-Based Polymer Composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-11-01 US disclosed
EP-2484701-A1 PRODUCTION METHOD FOR MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND MODIFIED CONJUGATED DIENE POLYMER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2012-08-08 EP disclosed