Sugi Predict

Sugi Predict / Compounds / SCHEMBL2930832

SCHEMBL2930832

SCHEMBL2930832

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)Oc1cc(-c2ccccc2)n[nH]1)[C@@H](C)O)B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 19/20 0.57
▸ PSMB11 A5LHX3 6/20 0.57
▸ PSMA7 O14818 6/20 0.57
▸ PARP1 P09874 6/20 0.57
▸ PSMB1 P20618 6/20 0.57
▸ PSMA1 P25786 6/20 0.57
▸ PSMA2 P25787 6/20 0.57
▸ PSMA3 P25788 6/20 0.57
▸ PSMA4 P25789 6/20 0.57
▸ PSMB8 P28062 6/20 0.57
▸ PSMB9 P28065 6/20 0.57
▸ PSMA5 P28066 6/20 0.57
▸ PSMB4 P28070 6/20 0.57
▸ PSMB6 P28072 6/20 0.57
▸ PSMB10 P40306 6/20 0.57
▸ PSMB3 P49720 6/20 0.57
▸ PSMB2 P49721 6/20 0.57
▸ PSMA6 P60900 6/20 0.57
▸ PSMA8 Q8TAA3 6/20 0.57
▸ PSMB7 Q99436 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13079073 0.89 PSMB5 (0.63) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2931822 0.87 PSMB5 (0.58) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2927497 0.86 PSMB5 (0.58) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2933171 0.86 PSEN1 (0.58) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2931289 0.85 PSMB5 (0.58) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2933121 0.85 PSMB5 (0.56) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2932867 0.85 PSMB5 (0.58) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2933650 0.84 PSMB5 (0.59) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2934011 0.83 PSMB5 (0.59) PSMB5PSMB11PSMA7PARP1PSMB1
SCHEMBL2935034 0.83 PSMB5 (0.59) PSMB5PSMB11PSMA7PARP1PSMB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1846424-B1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2010-01-27 — — EP claimed