SCHEMBL29308375

SCHEMBL29308375

CC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C1CCCN1)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 4/20 0.38
▸ TERT O14746 1/20 0.37
▸ CALCRL Q16602 1/20 0.37
▸ PRCP P42785 2/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.32
▸ REN P00797 1/20 0.32
▸ MAPK8 P45983 1/20 0.32
▸ MAPK9 P45984 1/20 0.32
▸ MAPK10 P53779 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308198 0.92 TERT (0.40) KEAP1TERTPRCPMEN1KMT2A
SCHEMBL29308356 0.92 TERT (0.40) KEAP1TERTCALCRLPRCPMEN1
SCHEMBL29308374 0.90 TERT (0.39) KEAP1TERTPRCPMEN1KMT2A
SCHEMBL22018478 0.86 TERT (0.41) KEAP1TERTCALCRLPRCPMEN1
SCHEMBL22019122 0.84 TERT (0.40) KEAP1TERTCALCRLPRCPMEN1
SCHEMBL22019453 0.84 TERT (0.42) KEAP1TERTPRCPMEN1KMT2A
SCHEMBL29308671 0.83 TERT (0.41) KEAP1TERTPRCPMEN1KMT2A
SCHEMBL29308397 0.83 TERT (0.39) TERTPRCPMEN1KMT2ADPP7
SCHEMBL29575779 0.81 CALCRL (0.49) KEAP1CALCRLMAPK8MAPK9MAPK10
SCHEMBL29836059 0.80 CALCRL (0.46) KEAP1CALCRLMAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 KEAP1 1861/4885TERT 3410/4885CALCRL 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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