Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380534 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686272 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL20550737 | 0.81 | PTGS1 (0.52) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687404 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686939 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687310 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686268 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686927 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687409 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686941 | 0.81 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773735-B1 | CONJUGATE OF CYTOTOXIC DRUG AND PRODRUG FORM OF SAID CONJUGATE | SYNDIVIA (FR) | 2024-07-10 | — | — | EP | disclosed |