Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 5/20 | 0.43 |
| ▸ | WEE1 | P30291 | 6/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997621 | 1.00 | PKMYT1 (0.49) | PKMYT1SLC2A1PAK1WEE1TNK2 | |
| SCHEMBL30997676 | 0.89 | WEE1 (0.42) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL29310210 | 0.89 | WEE1 (0.42) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL29310117 | 0.84 | SLC2A1 (0.57) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL30997622 | 0.84 | SLC2A1 (0.57) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL29310236 | 0.82 | BTK (0.49) | PKMYT1SLC2A1WEE1TNK2SYK | |
| SCHEMBL29310230 | 0.82 | WEE1 (0.48) | SLC2A1WEE1TNK2SYK | |
| SCHEMBL30997635 | 0.81 | WEE1 (0.49) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL29310208 | 0.81 | WEE1 (0.49) | PKMYT1SLC2A1WEE1TNK2JAK2 | |
| SCHEMBL29310224 | 0.79 | SLC2A1 (0.41) | PKMYT1SLC2A1WEE1TNK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | WEE1, WEE2, DCLRE1B | PKMYT1 1740/4885SLC2A1 4591/4885PAK1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.