Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 5/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 6/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 6/20 | 0.38 |
| ▸ | JAK3 | P52333 | 4/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | CDK7 | P50613 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997643 | 1.00 | WEE1 (0.45) | WEE1FGFR4SLC2A1JAK2MAPK8 | |
| SCHEMBL30997653 | 0.86 | SLC2A1 (0.44) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL29310214 | 0.86 | SLC2A1 (0.44) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL29310215 | 0.86 | SLC2A1 (0.44) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL30997625 | 0.86 | SLC2A1 (0.44) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL29310222 | 0.84 | SLC2A1 (0.42) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL29310117 | 0.84 | SLC2A1 (0.57) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL30997622 | 0.84 | SLC2A1 (0.57) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL29310224 | 0.83 | SLC2A1 (0.41) | WEE1SLC2A1JAK2MAPK8MAPK9 | |
| SCHEMBL30997639 | 0.82 | SLC2A1 (0.47) | WEE1SLC2A1JAK2MAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | WEE1, WEE2, DCLRE1B | WEE1 1/4885FGFR4 3043/4885SLC2A1 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.