Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1540416 | 1.00 | BCL2L1 (0.49) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540223 | 1.00 | BCL2L1 (0.49) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540934 | 0.99 | BCL2L1 (0.50) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540545 | 0.97 | BCL2L1 (0.50) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540145 | 0.85 | TRIM24 (0.44) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1539986 | 0.84 | ALDH1A1 (0.42) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540415 | 0.84 | BCL2L1 (0.49) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540221 | 0.84 | BCL2L1 (0.49) | BCL2L1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1540189 | 0.84 | BCL2 (0.48) | BCL2L1ALDH1A1KDM4EMAPTBCL2 | |
| SCHEMBL1954917 | 0.83 | BCL2L1 (0.70) | BCL2L1SMN1; SMN2MAPTBCL2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |