Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313436 | 0.92 | POLQ (0.40) | POLQLIPELMNASLC6A3GAA | |
| SCHEMBL29313435 | 0.92 | POLQ (0.40) | POLQLIPESLC6A3 | |
| SCHEMBL29313390 | 0.92 | POLQ (0.40) | POLQLIPELMNATSHR | |
| SCHEMBL29313334 | 0.92 | POLQ (0.39) | POLQTRPA1LIPESLC6A3TACR1 | |
| SCHEMBL29313439 | 0.92 | POLQ (0.39) | POLQLIPESLC6A3 | |
| SCHEMBL29313298 | 0.90 | POLQ (0.43) | POLQLIPELMNAGAAMAPK1 | |
| SCHEMBL29313343 | 0.89 | POLQ (0.38) | POLQLIPELMNAGAAMAPK1 | |
| SCHEMBL29313384 | 0.89 | POLQ (0.38) | POLQLIPE | |
| SCHEMBL29313263 | 0.89 | POLQ (0.40) | POLQLIPE | |
| SCHEMBL29313294 | 0.88 | POLQ (0.39) | POLQLIPETACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |