Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 6/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313330 | 0.91 | POLQ (0.39) | POLQLIPE | |
| SCHEMBL29313298 | 0.89 | POLQ (0.43) | POLQLIPE | |
| SCHEMBL29313262 | 0.89 | POLQ (0.41) | POLQLIPE | |
| SCHEMBL29313436 | 0.88 | POLQ (0.40) | POLQLIPE | |
| SCHEMBL29313435 | 0.88 | POLQ (0.40) | POLQLIPE | |
| SCHEMBL29313380 | 0.88 | POLQ (0.36) | POLQAR | |
| SCHEMBL29313294 | 0.87 | POLQ (0.39) | POLQLIPE | |
| SCHEMBL29313439 | 0.87 | POLQ (0.39) | POLQLIPE | |
| SCHEMBL29313334 | 0.87 | POLQ (0.39) | POLQLIPE | |
| SCHEMBL29313327 | 0.87 | POLQ (0.37) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |