Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 4/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313612 | 0.89 | POLQ (0.38) | POLQLIPECMA1FFAR4 | |
| SCHEMBL29313613 | 0.88 | POLQ (0.38) | POLQCMA1FFAR4 | |
| SCHEMBL29313610 | 0.88 | POLQ (0.39) | POLQCMA1FFAR4 | |
| SCHEMBL29313663 | 0.87 | POLQ (0.36) | POLQCMA1 | |
| SCHEMBL29313664 | 0.84 | POLQ (0.35) | POLQ | |
| SCHEMBL29313667 | 0.83 | POLQ (0.34) | POLQLIPE | |
| SCHEMBL30847572 | 0.82 | POLQ (0.39) | POLQLIPECMA1 | |
| SCHEMBL29314473 | 0.82 | POLQ (0.39) | POLQLIPECMA1 | |
| SCHEMBL29313708 | 0.82 | POLQ (0.38) | POLQLIPE | |
| SCHEMBL31009145 | 0.81 | POLQ (0.44) | POLQLIPECMA1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |