Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313712 | 0.92 | POLQ (0.35) | POLQSLC5A1TACR1 | |
| SCHEMBL29313746 | 0.89 | POLQ (0.35) | POLQ | |
| SCHEMBL29313708 | 0.86 | POLQ (0.38) | POLQTACR1 | |
| SCHEMBL29313711 | 0.86 | TACR1 (0.36) | POLQTACR1 | |
| SCHEMBL29313743 | 0.86 | POLQ (0.35) | POLQ | |
| SCHEMBL29313703 | 0.85 | TACR1 (0.39) | POLQTACR1 | |
| SCHEMBL29313707 | 0.83 | TACR1 (0.39) | POLQTACR1 | |
| SCHEMBL29313670 | 0.82 | POLQ (0.35) | POLQTACR1 | |
| SCHEMBL29313695 | 0.82 | POLQ (0.37) | POLQ | |
| SCHEMBL29313744 | 0.82 | POLQ (0.38) | POLQTACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |