Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313751 | 0.90 | POLQ (0.39) | POLQTACR1MAPTRXFP1CMA1 | |
| SCHEMBL29313795 | 0.85 | POLQ (0.38) | POLQ | |
| SCHEMBL29313753 | 0.84 | POLQ (0.37) | POLQ | |
| SCHEMBL29313794 | 0.84 | POLQ (0.37) | POLQMAPTSMN1; SMN2 | |
| SCHEMBL29313799 | 0.84 | POLQ (0.37) | POLQ | |
| SCHEMBL29313701 | 0.83 | POLQ (0.37) | POLQMAPTRXFP1CMA1 | |
| SCHEMBL29313754 | 0.83 | POLQ (0.37) | POLQTACR1 | |
| SCHEMBL29313749 | 0.83 | POLQ (0.38) | POLQTACR1 | |
| SCHEMBL29313704 | 0.83 | POLQ (0.39) | POLQMAPTRXFP1CMA1 | |
| SCHEMBL29313744 | 0.82 | POLQ (0.38) | POLQTACR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |