Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313926 | 0.86 | POLQ (0.34) | POLQSCN9A | |
| SCHEMBL29313931 | 0.83 | MEN1 (0.31) | SCN9A | |
| SCHEMBL29313948 | 0.82 | POLQ (0.35) | POLQ | |
| SCHEMBL29313930 | 0.81 | GAA (0.32) | — | |
| SCHEMBL29313857 | 0.72 | POLQ (0.33) | POLQ | |
| SCHEMBL30847810 | 0.70 | POLQ (0.39) | POLQ | |
| SCHEMBL30847594 | 0.70 | POLQ (0.39) | POLQ | |
| SCHEMBL29313945 | 0.70 | POLQ (0.38) | POLQ | |
| SCHEMBL29313943 | 0.68 | GPBAR1 (0.34) | POLQSCN9A | |
| SCHEMBL30638941 | 0.59 | FSCN1 (0.51) | POLQRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |