Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313931 | 0.90 | MEN1 (0.31) | ECE1MEN1KMT2A | |
| SCHEMBL29313940 | 0.84 | S1PR1 (0.35) | S1PR1GPBAR1 | |
| SCHEMBL29313948 | 0.84 | POLQ (0.35) | S1PR1ECE1GPBAR1MEN1KMT2A | |
| SCHEMBL29313926 | 0.83 | POLQ (0.34) | ECE1GPBAR1 | |
| SCHEMBL29313928 | 0.81 | POLQ (0.33) | — | |
| SCHEMBL29313943 | 0.75 | GPBAR1 (0.34) | S1PR1GPBAR1MEN1KMT2A | |
| SCHEMBL29313859 | 0.72 | GAA (0.31) | GAA | |
| SCHEMBL29313964 | 0.68 | POLQ (0.33) | GAAMEN1KMT2A | |
| SCHEMBL29314053 | 0.67 | IMPDH2 (0.36) | GPBAR1 | |
| SCHEMBL29313937 | 0.66 | POLQ (0.42) | S1PR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |