Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313860 | 0.89 | POLQ (0.34) | — | |
| SCHEMBL29314312 | 0.87 | — | — | |
| SCHEMBL29314315 | 0.86 | — | — | |
| SCHEMBL29314318 | 0.84 | — | — | |
| SCHEMBL29314311 | 0.84 | GAA (0.30) | — | |
| SCHEMBL29314303 | 0.83 | POLQ (0.33) | L3MBTL1HDAC8 | |
| SCHEMBL29313859 | 0.78 | GAA (0.31) | — | |
| SCHEMBL29313863 | 0.77 | — | — | |
| SCHEMBL29313857 | 0.76 | POLQ (0.33) | — | |
| SCHEMBL29313852 | 0.71 | POLQ (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |