Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001568 | 0.83 | PIK3CD (0.42) | PIK3CGPIK3CDPIK3CAPARP1PARP2 | |
| SCHEMBL1001933 | 0.81 | PIK3CG (0.42) | PIK3CGPIK3CDPIK3CAPARP1PARP2 | |
| SCHEMBL13613670 | 0.81 | PIK3CD (0.42) | PIK3CGPIK3CDPIK3CAPARP1PARP2 | |
| SCHEMBL8271584 | 0.81 | PIK3CD (0.42) | PIK3CGPIK3CDPIK3CAPARP1PARP2 | |
| SCHEMBL17050433 | 0.77 | GRM5 (0.43) | PARP1MAPTHTR2A | |
| SCHEMBL29313927 | 0.75 | HTR2A (0.37) | PIK3CGPIK3CDPIK3CAPARP1PIK3R1 | |
| SCHEMBL29314052 | 0.75 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CAPIK3R1 | |
| SCHEMBL24469663 | 0.74 | PARP1 (0.56) | PIK3CGPIK3CDPIK3CAPARP1PARP2 | |
| SCHEMBL12546250 | 0.74 | MAPK1 (0.44) | PARP1MAPTHTR2A | |
| SCHEMBL1002883 | 0.74 | PARP1 (0.47) | PIK3CGPIK3CDPIK3CAPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | PI4KA, PIK3CA, PI4KB | PIK3CG 4/4885PIK3CD 5/4885PIK3CA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.