Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315005 | 0.88 | MET (0.46) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314988 | 0.87 | MET (0.49) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314974 | 0.85 | MET (0.47) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL22109173 | 0.83 | MET (0.54) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109177 | 0.80 | MET (0.47) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109192 | 0.79 | MET (0.40) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109390 | 0.79 | MET (0.75) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL30948868 | 0.79 | MET (0.75) | METPDE3BPDE3ACYP2C9PDE10A | |
| SCHEMBL22109185 | 0.78 | MET (0.45) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109175 | 0.78 | MET (0.52) | METPDE3BPDE3APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |