Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 9/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571468 | 0.81 | THRB (0.82) | THRBPKMMMP3ALDH1A1TP53 | |
| SCHEMBL27131524 | 0.78 | THRB (0.58) | THRBMAPTMMP3ALDH1A1TP53 | |
| SCHEMBL21148402 | 0.78 | THRB (0.75) | THRBPKMMAPTMMP3ALDH1A1 | |
| SCHEMBL21148401 | 0.78 | THRB (0.75) | THRBPKMMAPTMMP3ALDH1A1 | |
| SCHEMBL23553190 | 0.78 | THRB (0.75) | THRBPKMMAPTMMP3ALDH1A1 | |
| SCHEMBL25123478 | 0.78 | THRB (0.75) | THRBPKMMAPTMMP3ALDH1A1 | |
| SCHEMBL181487 | 0.77 | THRB (0.60) | THRBPPARGPPARAALDH1A1TP53 | |
| SCHEMBL16893759 | 0.77 | THRB (0.69) | THRBPPARGPPARAMMP3ALDH1A1 | |
| SCHEMBL16893724 | 0.77 | THRB (0.69) | THRBMMP3ALDH1A1TSHRHDAC3 | |
| SCHEMBL29315983 | 0.76 | THRB (0.56) | THRBMMP3HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |