Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29322031 | 1.00 | TDP1 (0.54) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL29316160 | 0.99 | TDP1 (0.52) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL29322010 | 0.96 | TDP1 (0.49) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL29316157 | 0.94 | TDP1 (0.51) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL13756115 | 0.90 | TDP1 (0.51) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL709455 | 0.89 | POLB (0.60) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL2468868 | 0.87 | HTT (0.64) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL953146 | 0.87 | HTT (0.64) | TDP1POLBAPEX1HTTL3MBTL1 | |
| SCHEMBL14275377 | 0.86 | POLB (0.61) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL29316148 | 0.85 | TSHR (0.55) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |