Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29316160 | 0.97 | TDP1 (0.52) | TDP1L3MBTL1POLBAPEX1HTT | |
| SCHEMBL29316163 | 0.96 | TDP1 (0.54) | TDP1L3MBTL1POLBAPEX1HTT | |
| SCHEMBL29322031 | 0.96 | TDP1 (0.54) | TDP1L3MBTL1POLBAPEX1HTT | |
| SCHEMBL29316157 | 0.95 | TDP1 (0.51) | TDP1L3MBTL1POLBAPEX1HTT | |
| SCHEMBL13756115 | 0.91 | TDP1 (0.51) | TDP1L3MBTL1POLBAPEX1HTT | |
| SCHEMBL29316150 | 0.87 | POLB (0.58) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL709455 | 0.85 | POLB (0.60) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL7102222 | 0.85 | TDP1 (0.59) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL14275377 | 0.84 | POLB (0.61) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL29316020 | 0.84 | TDP1 (0.54) | TDP1POLBAPEX1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |