Sugi Predict

Sugi Predict / Compounds / SCHEMBL2931630

SCHEMBL2931630

SCHEMBL2931630

Clc1ccc(N(Cc2ccccc2)C[C@@H]2CNC[C@H]2Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 11/20 1.00
▸ CTSD P07339 2/20 0.72
▸ CTSE P14091 2/20 0.72
▸ PGC P20142 2/20 0.72
▸ SLC6A2 P23975 6/20 0.64
▸ SLC6A4 P31645 6/20 0.64
▸ SLC6A3 Q01959 6/20 0.64
▸ GBA1 P04062 1/20 0.43
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2D6 P10635 2/20 0.40
▸ CYP2C9 P11712 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2931369 1.00 REN (1.00) RENCTSDCTSEPGCSLC6A2
SCHEMBL2931370 1.00 REN (1.00) RENCTSDCTSEPGCSLC6A2
SCHEMBL2937334 0.90 REN (0.81) RENCTSDCTSEPGCSLC6A2
SCHEMBL2937330 0.90 REN (0.81) RENCTSDCTSEPGCSLC6A2
SCHEMBL2938174 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2
SCHEMBL2932628 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2
SCHEMBL2934310 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2
SCHEMBL2934307 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2
SCHEMBL2937594 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2
SCHEMBL2931226 0.89 REN (0.79) RENCTSDCTSEPGCSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775460-A Process for preparing polyethylene polymerization catalyst SK新技术株式会社 2025-04-08 — — CN claimed
CN-116606391-B Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application 中国石油化工股份有限公司 2024-11-19 — — CN claimed
EP-4342918-A1 PROCESS FOR THE SYNTHESIS OF STERICALLY CROWDED AND SYNTHETICALLY CHALLENGING ALKYL ALKOXY SILANES USING ORGANOLITHIUM REAGENTS SABIC Global Technologies B.V. (NL) 2024-03-27 — — EP claimed
CN-116693728-A Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-09-05 — — CN claimed
CN-116693727-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-05 — — CN claimed
EP-3271433-A1 NOVEL SILOXANE POLYMER COMPOSITIONS AND THEIR USE BASF SE (DE) 2018-01-24 — — EP claimed
WO-2016146896-A1 NOVEL SILOXANE POLYMER COMPOSITIONS AND THEIR USE OPTITUNE OY (FI) 2016-09-22 — — WO claimed
EP-1836163-B1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN NOVARTIS AG (CH) 2010-09-22 — — EP claimed
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN BREITENSTEIN WERNER 2010-04-08 — — US claimed
EP-1836163-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN Novartis AG (CH) 2007-09-26 — — EP claimed
WO-2006066896-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN NOVARTIS AG (CH) 2006-06-29 — — WO claimed
CN-118974105-A Olefin polymerization catalyst comprising magnesium, titanium, epoxy compounds and internal electron donors such as compounds based on 1, 2-phenylene dibenzoate 格雷斯公司 2024-11-15 — — CN disclosed
EP-4342918-A1 PROCESS FOR THE SYNTHESIS OF STERICALLY CROWDED AND SYNTHETICALLY CHALLENGING ALKYL ALKOXY SILANES USING ORGANOLITHIUM REAGENTS SABIC Global Technologies B.V. (NL) 2024-03-27 — — EP disclosed
US-20190309100-A1 ALKOXY MAGNESIUM SUPPORTED OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2019-10-10 — — US disclosed
US-9541832-B2 Photosensitive resin composition, protective film and element having the same CHI MEI CORPORATION (TW) 2017-01-10 — — US disclosed
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN BREITENSTEIN WERNER 2010-04-08 — — US disclosed
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN BREITENSTEIN WERNER 2010-04-08 — — US disclosed
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN BREITENSTEIN WERNER 2010-04-08 — — US disclosed
EP-2130870-A1 ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER FILM, REFLECTIVE FILM AND REFLECTIVE PLATE MITSUBISHI PLASTICS, INC. (JP) 2009-12-09 — — EP disclosed
WO-2009060125-A1 CARBOSILANE POLYMER COMPOSITIONS FOR ANTI-REFLECTIVE COATINGS BRAGGONE OY (FI) 2009-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN REN, ACE, PEPD REN 1/4885CTSD 153/4885CTSE 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.