SCHEMBL29316405

SCHEMBL29316405

C[C@@H](Cc1c[nH]c2ccc(F)cc12)N[C@H](C)[C@@H](C)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.61
HTR2C P28335 1/20 0.61
NR3C1 P04150 1/20 0.55
GPR84 Q9NQS5 2/20 0.52
MPO P05164 13/20 0.51
SLC6A4 P31645 3/20 0.49
MTNR1A P48039 1/20 0.49
MTNR1B P49286 1/20 0.49
NOTUM Q6P988 1/20 0.49
TSHR P16473 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27837972 0.82 HTR2A (0.69) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL30457763 0.82 HTR2A (0.69) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL25397483 0.82 HTR2A (0.69) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL699832 0.82 HTR2A (0.73) HTR2AHTR2CGPR84MPOSLC6A4
SCHEMBL21292855 0.80 HTR2A (0.61) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL20425196 0.80 HTR2A (0.61) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL24912887 0.80 HTR2A (0.61) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL20242715 0.80 HTR2A (0.61) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL27220727 0.80 HTR2A (0.61) HTR2AHTR2CNR3C1GPR84MPO
SCHEMBL22923386 0.79 HTR2A (0.77) HTR2AHTR2CNR3C1GPR84MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239747-A1 Next Generation 5-HT2AR Agonists HUXLEY HEALTH, INC. (CA) 2024-07-18 US disclosed
US-20240239747-A1 Next Generation 5-HT2AR Agonists HUXLEY HEALTH, INC. (CA) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239747-A1 Next Generation 5-HT2AR Agonists OPRL1, HTR2A, HTR5A HTR2A 2/4885HTR2C 4/4885NR3C1 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.