Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.59 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.59 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197130 | 0.75 | YTHDF2 (0.59) | YTHDF2YTHDF3YTHDF1DAOMAPT | |
| SCHEMBL19583295 | 0.75 | YTHDF2 (0.59) | YTHDF2YTHDF3YTHDF1DAOMAPT | |
| SCHEMBL27909964 | 0.68 | YTHDF2 (0.50) | YTHDF2YTHDF3YTHDF1DAOMAPT | |
| SCHEMBL19583314 | 0.67 | YTHDF2 (0.48) | YTHDF2YTHDF3YTHDF1DAOMAPT | |
| SCHEMBL17112519 | 0.66 | YTHDF2 (0.47) | YTHDF2YTHDF3YTHDF1ALDH1A1KDM4E | |
| SCHEMBL22239460 | 0.65 | YTHDF2 (0.81) | YTHDF2YTHDF3YTHDF1DAOMAPT | |
| SCHEMBL1348693 | 0.64 | YTHDF3 (0.45) | YTHDF2YTHDF3YTHDF1ALDH1A1KDM4E | |
| SCHEMBL3527762 | 0.64 | — | — | |
| SCHEMBL29316764 | 0.64 | — | — | |
| SCHEMBL15427620 | 0.61 | YTHDF2 (0.47) | YTHDF2YTHDF3YTHDF1DAOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400497-A1 | 3CLPRO PROTEASE INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-07-17 | — | — | EP | disclosed |