Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | KHK | P50053 | 5/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821430 | 0.90 | HTR6 (0.45) | HTR6KHKHTR2C | |
| SCHEMBL1400723 | 0.90 | HTR6 (0.56) | HTR6KHKSLC18A3HTR2CHTR2B | |
| SCHEMBL31208620 | 0.90 | HTR6 (0.56) | HTR6KHKSLC18A3HTR2CHTR2B | |
| SCHEMBL27380381 | 0.85 | — | — | |
| SCHEMBL238942 | 0.85 | HTR6 (0.75) | HTR6KHKHTR2CHTR2BARG1 | |
| SCHEMBL1447785 | 0.85 | HTR6 (0.75) | HTR6KHKHTR2CHTR2BARG1 | |
| SCHEMBL223255 | 0.85 | HTR6 (0.75) | HTR6KHKHTR2CHTR2BARG1 | |
| SCHEMBL12730863 | 0.85 | — | — | |
| SCHEMBL9558262 | 0.85 | HTR6 (0.68) | HTR6KHKSLC18A3HTR2CHTR2B | |
| SCHEMBL12120302 | 0.84 | HTR6 (0.50) | HTR6KHKHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |