Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355659 | 0.90 | HSD17B3 (0.42) | HSD17B3HTR7HRH2HRH1MEN1 | |
| SCHEMBL10355660 | 0.90 | HSD17B3 (0.42) | HSD17B3HTR7HRH2HRH1MEN1 | |
| SCHEMBL18397231 | 0.78 | GSK3B (0.43) | L3MBTL1MEN1KMT2A | |
| SCHEMBL29539684 | 0.78 | GSK3B (0.43) | L3MBTL1MEN1KMT2A | |
| SCHEMBL29539403 | 0.76 | MEN1 (0.43) | L3MBTL1IDO1MEN1KMT2A | |
| SCHEMBL18397093 | 0.76 | MEN1 (0.43) | L3MBTL1IDO1MEN1KMT2A | |
| SCHEMBL21207698 | 0.75 | IDO1 (0.53) | L3MBTL1IDO1KMT2ANPC1 | |
| SCHEMBL20372049 | 0.75 | HSD17B3 (0.54) | HSD17B3HTR7L3MBTL1MEN1KMT2A | |
| SCHEMBL25331810 | 0.75 | CA12 (0.47) | L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL17663686 | 0.75 | IDO1 (0.44) | L3MBTL1IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795563-B1 | INDOLINE ANALOGS AND USES THEREOF | ONCTERNAL THERAPEUTICS INC (US) | 2024-07-17 | — | — | EP | disclosed |