Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355660 | 1.00 | HSD17B3 (0.42) | HSD17B3HRH2HRH1MAPTGAA | |
| SCHEMBL29317443 | 0.90 | HSD17B3 (0.49) | HSD17B3HRH2HRH1HTR7MEN1 | |
| SCHEMBL10355648 | 0.81 | KMT2A (0.41) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10355646 | 0.81 | KMT2A (0.41) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10355467 | 0.80 | MAPT (0.42) | MAPTGAACYP2C9PTGS1PTGS2 | |
| SCHEMBL10355466 | 0.80 | MAPT (0.42) | MAPTGAACYP2C9PTGS1PTGS2 | |
| SCHEMBL10460863 | 0.78 | MAPT (0.43) | MAPTGAACYP2C9ALDH1A1LMNA | |
| SCHEMBL9805447 | 0.78 | GAA (0.43) | MAPTGAACYP2C9ALDH1A1MEN1 | |
| SCHEMBL10460862 | 0.78 | MAPT (0.43) | MAPTGAACYP2C9ALDH1A1LMNA | |
| SCHEMBL9805435 | 0.78 | GAA (0.43) | MAPTGAACYP2C9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194153-B1 | PYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4684477-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0194153-A2 | Pyridine derivatives | Chisso Corporation (JP) | 1986-09-10 | — | — | EP | disclosed |