Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16381874 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TK1 | |
| SCHEMBL12831196 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TK1 | |
| SCHEMBL10201808 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TK1 | |
| SCHEMBL16381893 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL8288025 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL26623252 | 0.80 | CASP3 (0.35) | SMN1; SMN2CASP1CASP3CASP8TK1 | |
| SCHEMBL6200874 | 0.80 | CASP3 (0.35) | SMN1; SMN2CASP1CASP3CASP8TK1 | |
| SCHEMBL26623259 | 0.80 | CASP3 (0.35) | SMN1; SMN2CASP1CASP3CASP8TK1 | |
| SCHEMBL13139707 | 0.76 | TMEM97 (0.41) | CASP1CASP3CASP8 | |
| SCHEMBL7150924 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146906-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2024-07-11 | — | — | WO | disclosed |