Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317746 | 0.81 | MMP1 (0.48) | BCL9CTNNB1CNR2 | |
| SCHEMBL5799001 | 0.74 | PDE2A (0.43) | GAACNR2CNR1PDE2ACCKBR | |
| SCHEMBL5798996 | 0.74 | PDE2A (0.43) | GAACNR2CNR1PDE2ACCKBR | |
| SCHEMBL1767738 | 0.73 | CA1 (0.53) | GAACNR2CNR1PDE2ACCKBR | |
| SCHEMBL13407614 | 0.73 | MCL1 (0.51) | GAACNR2CNR1PDE2ACCKBR | |
| SCHEMBL1269555 | 0.73 | MCL1 (0.46) | GAACNR2CNR1CCKBRMCL1 | |
| SCHEMBL20256179 | 0.72 | MCL1 (0.52) | GAACCKBRMCL1PPARG | |
| SCHEMBL17069302 | 0.70 | PDE2A (0.50) | CNR2CNR1PDE2AMCL1HSD11B1 | |
| SCHEMBL21800169 | 0.70 | MCL1 (0.51) | GAACCKBRMCL1PPARG | |
| SCHEMBL29321248 | 0.70 | CA1 (0.48) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |