Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898275 | 0.78 | POLB (0.41) | ALDH1A1MAPK1TDP1POLBRAB9A | |
| SCHEMBL800895 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL24773112 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL27403227 | 0.72 | MAOB (0.50) | ALDH1A1KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24773107 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL22043164 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL522510 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL991531 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL24783659 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL24773106 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148104-A1 | COMBINATION THERAPY OF APELIN RECEPTOR AGONIST AND GLP-1 RECEPTOR AGONIST FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH WEIGHT GAIN | BioAge Labs, Inc. (US) | 2024-07-11 | — | — | WO | disclosed |