Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892914 | 1.00 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL29318686 | 1.00 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL27213856 | 1.00 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL30892950 | 0.90 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL27213935 | 0.90 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL27395306 | 0.90 | NR1H4 (0.43) | NR1H4P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL30892999 | 0.88 | NR1H4 (0.35) | NR1H4P2RX7HDAC4HDAC6 | |
| SCHEMBL29318671 | 0.88 | NR1H4 (0.35) | NR1H4P2RX7HDAC4HDAC6 | |
| SCHEMBL27213878 | 0.88 | NR1H4 (0.35) | NR1H4P2RX7HDAC4HDAC6 | |
| SCHEMBL30892963 | 0.88 | NR1H4 (0.43) | NR1H4P2RX7HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | NR1H4 94/4885P2RX7 4636/4885HDAC4 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.