Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 10/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27230840 | 1.00 | MCHR1 (0.42) | MCHR1HDAC4HDAC6EPHX2KCNH2 | |
| SCHEMBL27213901 | 1.00 | MCHR1 (0.42) | MCHR1HDAC4HDAC6EPHX2KCNH2 | |
| SCHEMBL27230795 | 0.90 | HDAC4 (0.46) | MCHR1HDAC4HDAC6EPHX2KCNH2 | |
| SCHEMBL27213743 | 0.90 | HDAC4 (0.46) | MCHR1HDAC4HDAC6EPHX2KCNH2 | |
| SCHEMBL27394713 | 0.88 | CNR2 (0.41) | HDAC4HDAC6CNR2CYP1A2CYP2C9 | |
| SCHEMBL29318607 | 0.88 | CNR2 (0.41) | HDAC4HDAC6CNR2CYP1A2CYP2C9 | |
| SCHEMBL30892975 | 0.88 | CNR2 (0.41) | HDAC4HDAC6CNR2CYP1A2CYP2C9 | |
| SCHEMBL30893003 | 0.84 | SMO (0.40) | MCHR1HDAC4HDAC6CYP1A2CYP2C9 | |
| SCHEMBL27395499 | 0.84 | SMO (0.40) | MCHR1HDAC4HDAC6CYP1A2CYP2C9 | |
| SCHEMBL27232597 | 0.84 | SMO (0.40) | MCHR1HDAC4HDAC6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | MCHR1 2949/4885HDAC4 450/4885HDAC6 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.