Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 14/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 14/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319709 | 0.77 | BCL9 (0.56) | BCL9CTNNB1PPARA | |
| SCHEMBL29318848 | 0.77 | BCL9 (0.53) | BCL9CTNNB1PPARA | |
| SCHEMBL29054055 | 0.77 | BCL9 (0.69) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL30350430 | 0.77 | BCL9 (0.69) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL30350484 | 0.75 | BCL9 (0.60) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL29054039 | 0.75 | BCL9 (0.60) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL29318451 | 0.74 | BCL9 (0.55) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL30350467 | 0.74 | BCL9 (0.55) | BCL9CTNNB1PPARAPROKR1 | |
| Hydrochloric Acid SCHEMBL29054047 | 0.73 | BCL9 (0.53) | BCL9CTNNB1PPARAPROKR1 | |
| SCHEMBL29321066 | 0.73 | BCL9 (0.67) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |