SCHEMBL29318848

SCHEMBL29318848

C=CC(C)(C)Oc1cccc(C2CCCN(C(=C)c3cccc(-c4ccc(C(C)C)cc4)c3)C2)c1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 19/20 0.53
CTNNB1 P35222 19/20 0.53
PPARA Q07869 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29319709 0.91 BCL9 (0.56) BCL9CTNNB1PPARA
SCHEMBL30350385 0.79 BCL9 (0.70) BCL9CTNNB1PPARA
SCHEMBL29318137 0.79 BCL9 (0.70) BCL9CTNNB1PPARA
SCHEMBL29318802 0.77 BCL9 (0.50) BCL9CTNNB1PPARA
SCHEMBL29318865 0.74 DRD3 (0.41) BCL9CTNNB1
SCHEMBL29320229 0.73 PPARA (0.42) BCL9CTNNB1PPARA
SCHEMBL4029935 0.71 PPARA (0.76) BCL9CTNNB1PPARA
SCHEMBL4198824 0.71 PPARA (0.76) BCL9CTNNB1PPARA
SCHEMBL4030613 0.71 PPARA (0.76) BCL9CTNNB1PPARA
SCHEMBL4031554 0.71 PPARA (0.76) BCL9CTNNB1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145931-A1 SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF 上海医药工业研究院有限公司 2024-07-11 WO disclosed