Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19553855 | 0.78 | ADORA2A (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19503597 | 0.78 | CDK1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19503305 | 0.78 | CDK1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL29388366 | 0.77 | CDK1 (0.67) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL11251829 | 0.71 | PNP (0.56) | CDK1CCNB1CCNE1CDK2P2RY1 | |
| SCHEMBL21279729 | 0.70 | ADORA2A (0.51) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL29386483 | 0.70 | CDK1 (0.60) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL14619182 | 0.70 | CDK1 (0.60) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19503611 | 0.69 | CDK1 (0.43) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL9114419 | 0.69 | CCNE1 (0.57) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |