Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034702 | 0.74 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL30273486 | 0.73 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL25036305 | 0.72 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL31028592 | 0.71 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL30274030 | 0.70 | DDB1 (0.64) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31028680 | 0.70 | CRBN (0.40) | DDB1CRBN | |
| SCHEMBL31425993 | 0.69 | CRBN (0.45) | DDB1CRBN | |
| SCHEMBL25034822 | 0.69 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL27451163 | 0.65 | CRBN (0.66) | DDB1CRBN | |
| SCHEMBL22526812 | 0.65 | CRBN (0.69) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | DDB1 294/4885CRBN 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.