SCHEMBL29319647

SCHEMBL29319647

CCn1cc(I)c(NC)n1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
LRRK2 Q5S007 1/20 0.36
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
COMT P21964 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27831848 0.76 RAB9A (0.38) CYP1A2LRRK2ALDH1A1KDM4ENPC1
SCHEMBL29343719 0.72
SCHEMBL24977207 0.72
SCHEMBL24828585 0.71
SCHEMBL24013869 0.71
SCHEMBL18390051 0.71 HTT (0.38) ALDH1A1KDM4ENPC1LMNAHTT
Ammonia Solution, Strong SCHEMBL28919773 0.69 HTT (0.37) ALDH1A1KDM4ENPC1LMNAHTT
SCHEMBL24937059 0.68 SMN1; SMN2 (0.33) ALDH1A1KDM4ENPC1HTTSMN1; SMN2
SCHEMBL21721470 0.68 HTT (0.33) ALDH1A1KDM4ENPC1HTTSMN1; SMN2
SCHEMBL26388989 0.68 HTT (0.33) ALDH1A1KDM4ENPC1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400497-A1 3CLPRO PROTEASE INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2024-07-17 EP disclosed