SCHEMBL29319726

SCHEMBL29319726

Oc1cc(O)cc(-c2ccc(F)c(C(F)(F)F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.55
AR P10275 4/20 0.45
MPL P40238 3/20 0.45
ABL1 P00519 3/20 0.45
ABCB1 P08183 3/20 0.45
BCR P11274 3/20 0.45
KMO O15229 2/20 0.44
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
PTPN7 P35236 1/20 0.40
DUSP3 P51452 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31030963 0.85 MPL (0.55) KIF11ARMPLKMO
SCHEMBL29320009 0.85 KIF11 (0.76) KIF11ABL1ABCB1BCR
SCHEMBL30977609 0.77 KIF11 (0.53) KIF11ARMPLKMOHSD17B1
SCHEMBL29319737 0.77 ABCB1 (0.54) KIF11ABL1ABCB1BCRHSD17B1
SCHEMBL156681 0.77 KIF11 (0.53) KIF11ARMPLKMOHSD17B1
Water SCHEMBL27486863 0.75 KIF11 (0.52) KIF11ARMPLKMOHSD17B1
SCHEMBL13906328 0.74 AR (0.59) KIF11ARMPLKMO
SCHEMBL14572658 0.74 KIF11 (0.47) KIF11ARMPLKMO
SCHEMBL13906292 0.73 MPL (0.49) KIF11ARMPLKMO
SCHEMBL28666553 0.73 KIF11 (0.46) KIF11ARMPLKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed